5-HT1A modulator 1 o-C8-NH2 hydrochloride [O-]C(=O)[C@H]1C[C@@H]1C(=O)C1C=CC(Cl)=C(Cl)C=1

[O-]C(=O)[C@H]1C[C@@H]1C(=O)C1C=CC(Cl)=C(Cl)C=1

5-dioxopyrrolidin-1-yl 3'

MGCD0103 binds to and inhibits Class 1 isoforms of HDAC

21(7):921-47

aureus strain 630 (a penicillinase-producing strain)

5-HT1A modulator 1 o-C8-NH2 hydrochloride [O-]C(=O)[C@H]1C[C@@H]1C(=O)C1C=CC(Cl)=C(Cl)C=15 HT1A modulator 1 displays very high affinities for the 5HT1A, adrenergic 1 and dopamine D2 receptor with IC50s of 2 0. 3 nM, 10 3 nM and 40 9 nM, respectively. Product information CAS Number: 142477 34 7 Molecular Weight: 383. 51 Formula: C21H25N3O2S Chemical Name: 6 {2 [4 (2 methoxyphenyl)piperazin 1 yl]ethyl} 3 methyl 2,3 dihydro 1,3 benzothiazol 2 one Smiles: CN1C(=O)SC2=CC(CCN3CCN(CC3)C3=CC=CC=C3OC)=CC=C12 InChiKey: RTHIBOYVHBRSHH UHFFFAOYSA N